Podcast # 468: Typhlitis
Show: Emergency Medical Minute
Educational Pearls:
- Tiflitis refers to the presence of enterocolitis in the setting of neutropenia - also known as neutropenic enterocolitis
- Commonly a result of chemotherapy for hematologic malignancies.
- The infection is usually polymicrobial/fungal and can lead to septic shock
- Usually presents with fever, abdominal pain, with associated GI complaints
- Workup includes CBC for the ANC (usually <500), and a CT abdomen (look for bowel thickening)
- Treatment typically with broad-spectrum antibiotics with or without anti-fungal agents
- Mortality can be as high as 50%
References
Cloutier RL. Neutropenic enterocolitis. Emerg Med Clin North Am. 2009 Aug;27(3):415-22. doi: 10.1016/j.emc.2009.04.002. PubMed PMID: 19646645.
Rodrigues FG, Dasilva G, Wexner SD. Neutropenic enterocolitis. World J Gastroenterol.2017 Jan 7;23(1):42-47. doi: 10.3748/wjg.v23.i1.42. Review. PubMed PMID: 28104979; PubMed Central PMCID: PMC5221285.
Summarized by Will Dewispelaere, MS3 | Edited by Erik Verzemnieks, MD
More From Current Show
Podcast 1025: Post intubation Sedation Contributor: Aaron Lessen, MD Educational Pearls: Experts suggest that anyone who is...
Listen Now Contributor: Taylor Lynch, MD Educational Pearls: Excessive caffeine intake can be dangerous. For normal adults, the toxicity level...
Listen Now Contributor: Aaron Lessen, MD Educational Pearls: Case review of a patient with recurrent episodes of syncope and shortness...
Listen Now Contributor: Taylor Lynch, MD Educational Pearls: When a patient who missed dialysis presents to the emergency department, our...
Listen Now Contributor: Travis Barlock, MD Educational Pearls: What is pulmonary edema? Pulmonary edema is the accumulation of fluid initially...
Listen Now Contributor: Alec Coston, MD Educational Pearls: Benign Paroxysmal Positional Vertigo (BPPV) Common inner ear condition that can cause...
Listen Now Contributor: Aaron Lessen, MD Educational Pearls: Blunt cerebrovascular injury (BCVI) BCVI is a traumatic injury to the carotid...
Listen Now Contributor: Aaron Lessen, MD Educational Pearls: Big question in cardiac arrest: is the rhythm shockable? Shockable: ventricular fibrillation...
Listen Now Related Episodes
No related episodes found.
