Kriben Govender (Honours Degree in Food Science & Technology) and James Shadrach (Honours Degree in Psychology) interview The Probiotic Advisor- Dr Jason Hawrelak on how to optimise your Gut Microbiome using DNA based Stool Testing, Diet, Prebiotics and Probiotics.

 

Dr Hawrelak is Head of Research at ProbioticAdvisor.com. His passion for gastrointestinal health, the GIT microbiota, and probiotics was ignited during the final year of his undergraduate training. Subsequently, Dr Hawrelak did his Honours (First Class) and PhD degrees in the areas of the gastrointestinal microbiota, irritable bowel syndrome, and the clinical applications of pre- and probiotics. He has written extensively in the medical literature on these topics – including 16 textbook chapters – and his research has been cited over 800 times. 

 

 

- The digestive disease epidemic and the associated causes

- What is the Gut Microbiome vs Gut Microbiota

- DNA Based Stool Testing

- How to interpret a Stool Testing Report

- Firmicutes, Bacteroidetes and Proteobacteria

- The negative effects of Proteobacteria endoxins/Lipopolysaccharides

- Strategies to reduce Proteobacteria genera

- Hydrogen sulfide gas producers - eg Desulfovibrio, Bilophila 

- Methane producing Archae- Methanobrevibacter. smithii

- Using Prebiotics to decrease abundance of Pathobionts - Partially Hydrolysed Guar Gum, fructo-oligosaccharides (FOS) Inulin, Lactulose, Galacto-oligosaccharides (GOS), Acacia Fibre

- What are Short Chains Fatty acids, eg Butyrate, Acetate, Propionate

- Impact of Bile Acid Supplements

- Peace Keeping Bacteria- Lactobacilli, Bifidobacteria, Akkermansia

- Leaky Gut

- Increasing levels of the Peace Keeping to improve gut integrity

- Beneficial Butyrate Producing Bacteria

- Gut healing properties of Butyrate

- Foods that feed good bacteria- polyphenols, resistant starch

- Exogenous Butyrate supplementation

- Gut Dybiosis and Mental Health

- Endotoxin, brain inflammation and the link to depression/ anxiety

- Foods/ Diets to avoid to prevent depression and anxiety

- The importance of fibre for health and mental health

- The impact of sleep on microbiome diversity

- The synergistic impact of poor diet and sleep deprivation

- What is Small Intestinal Overgrowth (SIBO)?

- SIBO and the oral microbiome

- Is there a place for a mouth probiotic?

- The negative impact of proton pump inhibitors

- Lactobacillus reuteri DSM 17938 for gum disease, and SIBO

- Helminthic Therapy, hook worms and celiac disease

- Are parasites a problem? Giardia, Blastocystic hominis, Dientamoeba fragilis

- The role of commensal protozoa and fungi

- Are probiotics effective after a course of antibiotics? (study discussed in a previous podcast - Episode 3 - The Truth about Probiotics)

- How to effectively use probiotics?

- Bifidobacterium lactis HN019 and gut transit time

- Digestive enzymes, Hydrochloric Acid

   

   

 

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