COVID-19 Associated Glomerular Disease

In this episode of the Better Edge Podcast, Aneesha Shetty, MD, MPH, assistant professor of Medicine in the Division of Nephrology and Hypertension, discusses finding from a recent case report published in the Journal of the American Society of Nephrology.

This study highlights an emerging COVID-19 related kidney disease that is characterized by podocytopathy and/or collapsing FSGS. In investigating this phenomenon among six patients with proteinuria collapsing FSGS and COVID-19 infection, it was observed that the patients were all of recent African ancestry. This led to further investigation into whether this kidney disease is associated with the high risk APOL1 genotype. This association may help predict how a patient will do with COVID-19, their needs after infection recovers, and sheds light on APOL1 genotypes and kidney disease.